
Inoculation against smallpox aroused a storm of protest from divines. The Sorbonne pronounced against it on theological grounds. One Anglican clergyman published a sermon in which he said that Job's boils were doubtless due to inoculation by the Devil, and many Scottish ministers joined in a manifesto saying that it was "endeavouring to baffle a Divine judgment." However, the effect in diminishing the death-rate from smallpox was so notable that theological terrors failed to outweigh fear of the disease.
More info.: https://russell-j.com/beginner/RS1935_04-180.HTM